Longitudinal single-subject neuroimaging study reveals effects of daily environmental, physiological, and lifestyle factors on functional brain connectivity.

Our behavior and mental states are constantly shaped by our environment and experiences.However, little is known about the response of brain functional connectivity to environmental, physiological, and behavioral changes on different timescales, from days to months.This gives rise to an urgent need for longitudinal studies that collect high-frequen

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Challenges and opportunities in the immunotherapy era: balancing expectations with hope in small-cell lung cancer

Small-cell lung cancer (SCLC) is a biologically aggressive subtype of lung cancer, a lethal disease characterized by rapid tumor growth, early relapse, a strong tendency for early widespread metastasis, and high genomic instability, making it a formidable foe in modern oncology practice.While the management of non-SCLC has been revolutionized in th

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Prolonged-release melatonin for insomnia – an open-label long-term study of efficacy, safety, and withdrawal

Patrick Lemoine1, Doron Garfinkel2, Moshe Laudon3, Tali Nir3, Nava Zisapel3,41The Clinique Lyon-Lumière, Meyzieu, France; 2Geriatric-Palliative Department, Shoham Geriatric Medical Center, Pardes Hanna, Israel; 3Neurim Pharmaceuticals Ltd, Tel-Aviv, Israel; 4Department of Neurobiology Faculty of Life Sciences, Tel Aviv University, Tel Av

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